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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DAPK1 All Species: 23.33
Human Site: S734 Identified Species: 51.33
UniProt: P53355 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53355 NP_004929.2 1430 160073 S734 N S S R F P P S P L A S K P T
Chimpanzee Pan troglodytes XP_001140200 1430 160025 S734 N S S R F P P S P L A S K P T
Rhesus Macaque Macaca mulatta XP_001084634 1430 160024 S734 N S S R F P P S P L A S K P T
Dog Lupus familis XP_541259 1430 159848 S734 N S T R F P P S P L A S K P A
Cat Felis silvestris
Mouse Mus musculus Q80YE7 1442 161423 S734 N S T R F P P S P L A A K P T
Rat Rattus norvegicus O88764 448 51431
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026784 974 109076 I348 D S F V M K A I I H A I N D D
Frog Xenopus laevis NP_001086727 1427 159871 S734 N S S R F P S S P L T A K T V
Zebra Danio Brachydanio rerio NP_001093460 1439 159594 V734 V R H P A S P V T S K P A V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_490840 1425 158950 S729 H S S R G I S S F L E S V T R
Sea Urchin Strong. purpuratus XP_780774 1084 119703 E457 S E V T R G I E F T H G T I P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.3 95.5 N.A. 94.3 24.2 N.A. N.A. 60.7 86 74.7 N.A. N.A. N.A. 34.5 29.5
Protein Similarity: 100 99.9 99.7 97.9 N.A. 97.5 28.8 N.A. N.A. 65.8 93.8 87.2 N.A. N.A. N.A. 54.4 45.9
P-Site Identity: 100 100 100 86.6 N.A. 86.6 0 N.A. N.A. 13.3 66.6 6.6 N.A. N.A. N.A. 40 0
P-Site Similarity: 100 100 100 93.3 N.A. 100 0 N.A. N.A. 20 73.3 13.3 N.A. N.A. N.A. 46.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 10 0 0 0 55 19 10 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % D
% Glu: 0 10 0 0 0 0 0 10 0 0 10 0 0 0 0 % E
% Phe: 0 0 10 0 55 0 0 0 19 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 10 0 0 0 0 0 10 0 0 0 % G
% His: 10 0 10 0 0 0 0 0 0 10 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 10 10 10 0 0 10 0 10 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 10 0 55 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 64 0 0 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 55 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 10 0 55 55 0 55 0 0 10 0 46 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 0 64 10 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 10 73 46 0 0 10 19 64 0 10 0 46 0 0 10 % S
% Thr: 0 0 19 10 0 0 0 0 10 10 10 0 10 19 37 % T
% Val: 10 0 10 10 0 0 0 10 0 0 0 0 10 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _